I have been able to replicate this nearly 100% of the time.
Each time I have set up a new Ubuntu 18.04 and WordOps installation from scratch, everything installed well, and the WordOps dashboard was installed and could be accessed at 22222.
If I perform an update on a former EasyEngine installation, while it completes all the stack installs and stack --admin installations, proceeding to the 22222 location gives the same "403 Forbidden" message, and any of the dashboard features are (obviously) inaccessible.
What options do I have to fix this?
On servers with 5-6 sites installed, I backed up each individual site, reformatted and reinstalled, and manually reinstalled. This is not an option that I want to consider with sites with 25-50 sites on it.